Marion Buckwalter, MD, PhD, & Maarten Lansberg, MD, PhD, developed the Stroke Collaborative Action Network, or SCAN, which brings together clinical & research expertise from across the School of Medicine, Stanford Health Care & Stanford University, to understand the mechanisms of stroke recovery & develop new treatments. These efforts yielded the highest performing communication brain-machine interfaces demonstrated to date. In this 1:2:1 podcast, Greg Albers, director of the Stanford Stroke Center, joins host Paul Costello in conversation about the latest in stroke research. A graduate of Harvard School of Medicine, Dr. Steinman has been on the Stanford faculty since 1980. Clinical and research efforts have focused on promoting functional recovery after stroke. Dr. The Zhao lab studies the protective effects of ischemic postconditioning and the underlying protective mechanisms against stroke. Â. Dr. Steinberg is a neurosurgeon and basic and clinical scientist. Under his guidance, the Stroke Center has trained more than 40 clinical stroke specialists; many of these individuals are directing stroke centers at academic institutions … Her laboratory is very interested in both acute response to stroke, and factors that affect delayed plasticity, including effects of inflammation on neurogenesis, and the role of organelle interaction and the chaperone network in both acute response and plasticity. She is the Deputy Director of the Wu Tsai Neurosciences Institute, co-founded and now co-leads the Stroke Collaborative Action Network, and is the co-founder of the Stroke Recovery Program at Stanford. Funded Research Project: Stroke Collaborative Action Network. Current they are working on movement control in isometric environments aims to create new methods for rehabilitating chronic stroke patients. Buckwalter is a leader in stroke research and directs several clinical stroke initiatives at Stanford. His research addresses how large sets of genes are turned on or off together, which is important in normal development, cancer, and aging. Consistency and repetition are key to activating neuroplasticity after stroke. Paralysis (inability to move some parts of the body), weakness, or both on one side of the body. Trouble controlling or expressing emotions. In particular, I am interested in imaging neuroinflammation, microglial activation, neurodegeneration, cognitive decline, and neurogenesis using positron emission tomography (PET). Dr. Zaharchuk's research focuses on improved functional imaging of the brain following stroke, using both MRI and CT methods.  In particular, his group in collaboration with many others from the Departments of Neurology and Neurosurgery have focused on developing improved methods for assessing quantitative blood flow and oxygenation measurement in the brain, for identifying and quantifying the impact of collateral blood flow, and for measuring cerebrovascular reserve in the brain following a vasodilatory challenge (“brain stress test”).  His research spans from basic MR sequence development to clinical-translational application of these techniques to stroke patients.Â. StrokeCog is focused on cognitive problems after stroke. Prior to coming to Stanford, she was a researcher at the VA Palo Alto Medical Center and served as Director of the Neuropsychology Area of Emphasis at Palo Alto University. As neurology director of our Neuro Neonatal Intensive Care Unit, and in her clinical research, she investigates markers of early brain injury, and how they can identify candidates for neuroprotective treatments. Symptoms and signs of internal capsule stroke include weakness of the face, arm, and/or leg (pure motor stroke). He has chaired multiple consensus panels that have published national and international guidelines for stroke treatment and prevention. Their therapeutic targets are adrenergic receptors, lysosome proteases (cathepsins) and activity dependent transcription factor (Npas4). His interest is in using advanced functional neuroimaging tools to define causal neural circuit pathways in the brain in health and disease. ITV. P… Stanford Neuroscience Health Center. Outside of academics, his passions include playing tennis, learning new musical pieces on the cello, and exploring different … George PM(1), Bliss TM(2), Hua T(2), Lee A(3), Oh B(4), Levinson A(4), Mehta S(5), Sun G(2), Steinberg GK(6). Dr. Lee completed her pediatric neurology residency at Stanford in 2015 then joined the Stanford Stroke Center as a vascular neurology fellow.  Following her fellowship she began a faculty position at Stroke Center as an Assistant Professor.  Dr. Lee is board-certified in neurology with special qualification in child neurology, and attends on both the adult stroke service as well as the pediatric neurology service.  Dr. Lee is the Associate Director of the Stroke Center’s Telestroke Program. She really grew past some of her challenges.” Sarah struggled more when she was younger, … Investigators at the Stanford University School of Medicine have shown that removing a matched set of molecules that typically help to regulate the brain’s capacity for forming and eliminating connections between nerve cells could substantially aid recovery from stroke even days after the event.  A multi-disciplinary team of physiatrists, stroke neurologists, stroke nurses, physical therapists, occupational therapists, speech therapists, neuropsychologists, and social workers works together to provide the best care possible for our patients. Many skilled professionals are part of the rehabilitation team, including any/all of the following: Stroke Rehabilitation Prince is a neurologist and basic neuroscientist.  His work focuses on cellular and circuit abnormalities following focal cortical injuries and novel agents that may prevent maladaptive changes in neuronal and circuit structure and function. The CHARM lab designs and studies haptic systems using both analytical and experimental approaches. This investigation leverages multichannel electrode arrays to gather a neural population estimate of the state of the brain. He regularly lectures on his research in the U.S. and abroad. 1) What are the changes in cortical microcircuits that occur in peri-infarct regions that promote functional recovery, specifically with a focus on GABA receptors and a potential new therapeutic approach.  2) What are the changes in regions distal to the stroke, yet connected to the peri-infarct region, such as the thalamus that contribute to adaptive (functional recovery) and/or maladaptive (post-stroke epilepsy) circuit changes.  Relatedly, are there specific subcircuits implicated in epilepsy that could be focally targeted for novel therapies. StrokeCog is an extension of the Stroke Collaborative Action Network (SCAN) Big Idea project and is a key component of the Stanford Stroke Recovery Program. Their interests include minimally invasive surgery/ percutaneous interventions and robots to enable neuroscience research/rehabilitation. 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